At the beginning of 2020, the first cases of atypical pneumonia appeared in Wuhan, which then spread around the world resulting in the declaration of a pandemic of the Covid-19 virus by the World Health Organization. Traumatic events such as pandemics can have a negative effect on people's mental health, which can lead to increased consumption of addictive substances. The aim of this research is to examine the frequency of alcohol and addictive substances (drugs) consumption, as well as the connection between alcohol and addictive substances consumption with levels of anxiety, depression and life satisfaction, and to examine to what extent gender, age, depression, anxiety and life satisfaction explain alcohol consumption and drugs of addiction as a way of dealing with students' problems during the Covid-19 pandemic. 935 students of the University of Rijeka (212 men, 710 women, 13 unspecified) in the age range of 18 to 28 years, with an average age of 21.65 (SD) participated in the research. The Stress, Anxiety and Depression scale (DASS-21) was used for the purposes of the research, together with Alcohol and Drug Consumption Scale, the Questionnaire on Life Satisfaction and the Questionnaire on the Frequency of Alcohol and Drug Consumption. The survey was conducted in an online format using the Google Forms platform. Half of the students consumed addictive substances in the same quantities before and during the pandemic, while around 40% of them stated that they reduced their consumption during the pandemic. The level of depression is statistically significantly positively related to the consumption of cannabis, while no statistically significant relationship was obtained between the level of depression and the consumption of alcohol and stimulants, nor between the level of anxiety and life satisfaction with the consumption of alcohol, cannabis and stimulants. Nevertheless, it was found that students who stated that they consumed higher levels of alcohol/drugs during the pandemic had a statistically significantly higher level of anxiety and depression and a lower level of life satisfaction than students who consumed them in equal or smaller quantities compared to the time before the pandemic . Significant predictors for alcohol and drug consumption, as a way of coping with problems, were gender, level of depression and level of anxiety. The results obtained from this research confirm the connection between alcohol consumption and addictive substances as a way of coping with problems and psychological symptoms during the pandemic and provide a basis for further research on the same or similar topics.